Basic Principels of Peptide

Peptide is the condensation of two Alpha amino acid to form a dipeptide, bond between two alpha amino acids called peptide bond.
Amino acids can be covalently bonded together into a polymer by the formation of a amide bond (the peptide bond) between the alpha carboxyl group of one Amino acids and the alpha-amino of the next Amino acids.
A molecule of water is eliminated for each peptide bond formed and the products is called a peptide (e.g. dipeptide below). The portion of the Amino acids left in the peptide is terned an amino acid residue.

         

What is Peptide?

  Basic Principles of Peptide
   
       

 

The resulting Co (Called as Carboxyl)-NH (Called as Amide Group) linkage is known as peptide bond. Polymen composed of two, three, a few (3~10) and many amino acids residue are known, respectively, dipeptide, tripeptide, oligopeptide and polypeptide.
Proteins are molecules that consists of one or more polypeptide chains.

A molecule containing two amino acids joined by a peptide bond is a Dipeptide; one with three amino acids held together by two peptide bonds is a Tripeptide; four is a Tetrapeptide; etc. In general, Peptides contain 12 or fewer amino acid residues. An Oligopeptide contains between 12 and 20 amino acids and a Polypeptide contains greater than 20 amino acids. Twenty appears to be a magic number with respect to peptide/protein structure. Oligopeptides with 20 or fewer amino acids do not fold into, do assume a single low energy conformation, rather they exist in numerous random shapes. Molecules with greater than 20 amino acids very often fold into a single stable conformation, a single low energy conformation. The terms polypeptide and protein are often used interchangeably. However, the term protein is often reserved for molecules that perform some cellular function.